Tracing Brain Circuits For Mental Health

Neuroscience research needs help from many fields including engineering Dr Talia Lerner describes some of the engineering tools that she uses to study neural circuits in animal models especially involving dopamine She is a professor and basic science researcher at Northwestern University in Chicago and she studies these circuits in the hopes of improving mental health diagnoses and treatments Dr Lerner also shares her thoughts on what doctors scientists and engineers will tackle in future neuroscience work Related to this episode Dr Talia Lerner s lab The Lerner Lab http lernerlab org Videos of neurons visualized with new techniques http lernerlab org research Article on some common genetic links among depression schizophrenia autism and other conditions http bigthink com 21st-century-spirituality researchers-just-discovered-a-genetic-link-between-alcoholism-autism-bipolar-disorder-depression-and-schizophrenia Neurotransmitters such as glutamate on Wikipedia https en wikipedia org wiki Neurotransmitter Neuromodulators such as serotonin dopamine on Wikipedia https en wikipedia org wiki Neuromodulation Synapses or neuronal connections on Wikipedia https en wikipedia org wiki Synapse Action potentials or neuronal signals on Wikipedia https en wikipedia org wiki Action potential Karl Deisseroth s Lab at Stanford https web stanford edu group dlab Optogenetics resources https web stanford edu group dlab optogenetics index html GFP green fluorescent protein at Connecticut College https www conncoll edu ccacad zimmer GFP-ww GFP-1 htm Recombinant DNA at Khan Academy https www khanacademy org science biology biotech-dna-technology dna-cloning-tutorial v dna-cloning-and-recombinant-dna CLARITY resources http clarityresourcecenter org Article on the history of hydrogels http www jbiomeds com biomedical-sciences history-and-applications-of-hydrogels php aid 7218 NeuWrite West formerly Stanford Neuroblog http www neuwritewest org Berkeley Science Review science news http berkeleysciencereview com Carry the One Radio podcast http www carrytheoneradio com Viral neuronal tracing on Wikipedia https en wikipedia org wiki Viral neuronal tracing Article on using the engineered rabies virus against brain cancer http www sciencemag org news 2017 02 how-stop-brain-cancer-rabies Ed Callaway neuroscientist http callaway salk edu Ian Wickersham neuroscientist http wickershamlab org ian-wickersham Biosafety levels from the Centers for Disease Control and Prevention https www cdc gov training QuickLearns biosafety Our closing music is Late for School by Bleeptor used under a Creative Commons Attribution License https creativecommons org licenses by 4 0 Subscribe and find more podcast information at http www k12engineering net Support Pios Labs with regular donations on Patreon https www patreon com pioslabs or send one-time contributions by buying us coffee https ko-fi com pioslabs Thanks to our donors and listeners for making the show possible The K12 Engineering Education Podcast is a production of Pios Labs http www pioslabs com Click here to visit this podcast episode